It is a common sense that no sudden change of fluid properties happens in small-scale hydrodynamics. With low Reynolds number and incompressible flow conditions, micro/nanofluidics often enjoy stable Laminar flows, of course, without any phase changes. However, recent works reported phenomenological evidence of high-energy flows (e.g., turbulence, cavitation, and sonoluminescence) even in small-scale platforms. In this nascent research field, we aim to discover the effects of long-range interactions (e.g. electrodynamic, electrostatic, and polar interactions) on high-energy flows in a small-scale “bounded” condition. Referred to by Feynman, yet it is only recently that the intricacies of long-range interactions have merged in various areas unexpectedly. Until now, these interactions have been concerned as free boundary conditions with given properties. In a small-scale system, however, we can actively control the long-range interactions by adjusting the electro/mechanical/chemical properties of channel walls.